Table A1.
Mean cartilage thickness of the distinct subregions of the medial and lateral femur and tibia as a function of loading. Mean ± standard deviation (mm) (mean percentage change versus δ0 (%)). Statistical analysis was performed using repeated measures ANOVA and statistically significant findings are highlighted in bold type. Abbreviations: central medial femur (cMF), central lateral femur (cLF), medial tibia (MT), lateral tibia (LT). Please refer to Table 2 for additional details on table organization.
| Compartment | Region | Subregion | δ0 | δvar1 or vlg1 | δvar2 or vlg2 | δvar3 or vlg3 | p-Value |
|---|---|---|---|---|---|---|---|
| Medial Compartment | Tibia | Central subregion of MT | 2.14 ± 0.39 | 2.10 ± 0.37 (−1.9) | 2.06 ± 0.35 (−3.6) | 2.04 ± 0.35 (−4.5) | 0.002 |
| External subregion of MT | 1.25 ± 0.26 | 1.21 ± 0.29 (−3.2) | 1.18 ± 0.29 (−5.8) | 1.20 ± 0.31 (−4.6) | <0.001 | ||
| Internal subregion of MT | 1.79 ± 0.22 | 1.76 ± 0.20 (−1.7) | 1.73 ± 0.20 (−3.4) | 1.73 ± 0.20 (−3.4) | <0.001 | ||
| Anterior subregion of MT | 1.54 ± 0.19 | 1.51 ± 0.18 (−1.9) | 1.52 ± 0.19 (−1.4) | 1.50 ± 0.20 (−2.6) | 0.124 | ||
| Posterior subregion of MT | 1.30 ± 0.22 | 1.27 ± 0.19 (−2.6) | 1.25 ± 0.20 (−4.2) | 1.26 ± 0.21 (−3.4) | 0.104 | ||
| Femur | Central subregion of cMF | 1.93 ± 0.40 | 1.90 ± 0.44 (−1.3) | 1.89 ± 0.44 (−2.0) | 1.87 ± 0.46 (−2.8) | 0.002 | |
| External subregion of cMF | 1.20 ± 0.29 | 1.17 ± 0.30 (−2.4) | 1.17 ± 0.30 (−2.8) | 1.14 ± 0.30 (−5.3) | <0.001 | ||
| Internal subregion of cMF | 1.62 ± 0.45 | 1.62 ± 0.46 (−0.1) | 1.60 ± 0.45 (−1.5) | 1.61 ± 0.45 (−1.0) | 0.011 | ||
| Lateral Compartment | Tibia | Central subregion of LT | 3.06 ± 0.71 | 3.02 ± 0.64 (−1.2) | 3.00 ± 0.67 (−1.7) | 2.97 ± 0.64 (−2.9) | 0.256 |
| External subregion of LT | 1.44 ± 0.20 | 1.44 ± 0.19 (−0.1) | 1.40 ± 0.21 (−2.8) | 1.40 ± 0.21 (−2.8) | 0.303 | ||
| Internal subregion of LT | 1.91 ± 0.36 | 1.89 ± 0.39 (−1.1) | 1.90 ± 0.39 (−0.3) | 1.89 ± 0.38 (−1.3) | 0.426 | ||
| Anterior subregion of LT | 1.66 ± 0.28 | 1.65 ± 0.26 (−1.0) | 1.64 ± 0.27 (−1.6) | 1.63 ± 0.29 (−2.2) | 0.141 | ||
| Posterior subregion of LT | 1.64 ± 0.39 | 1.67 ± 0.38 (1.9) | 1.65 ± 0.39 (0.4) | 1.61 ± 0.36 (−2.0) | 0.103 | ||
| Femur | Central subregion of cLF | 2.19 ± 0.44 | 2.19 ± 0.36 (0.1) | 2.16 ± 0.36 (−1.6) | 2.18 ± 0.36 (−0.7) | <0.001 | |
| External subregion of cLF | 1.52 ± 0.28 | 1.50 ± 0.28 (−1.1) | 1.46 ± 0.27 (−3.7) | 1.47 ± 0.26 (−3.1) | <0.001 | ||
| Internal subregion of cLF | 1.67 ± 0.34 | 1.68 ± 0.32 (0.5) | 1.67 ± 0.33 (−0.2) | 1.68 ± 0.31 (0.6) | 0.288 |