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. 2021 Aug 17;10(8):2115. doi: 10.3390/cells10082115

Figure 4.

Figure 4

Effects of metformin on endothelial permeability. We assessed the dose-response relationship of metformin on the leakage of human brain microvascular endothelial cells, cultured at the indicated conditions (Glu: glucose; Mann: mannitol); *: p < 0.05 vs. Glu 5 mM; #: p < 0.05 vs. Vehicle.