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. 2021 Aug 3;11(8):1144. doi: 10.3390/biom11081144
↓ΔΨm mitochondrial membrane potential depolarization
NO nitric oxide
OH hydroxyl radical
4-HNE 4-hydroxynonenal
α-KΓ Alpha-ketoglutarate
α-KΓΔH alpha-ketoglutarate dehydrogenase
ACAD10 acyl-CoA dehydrogenase family member 10
ACS acyl-CoA synthetase
Acn aconitase
AGE advanced glycation end products
AKR1A1 aldo-keto reductase family 1 member A1
AKI acute kidney injury
AMPK adenosine monophosphate (AMP)-activated protein kinase
Ang II angiotensin II
Arg arginine
ATP adenosine triphosphate
ATR-1 angiotensin type 1 receptor
Bcl-2 B cell lymphoma 2
BUN blood urea nitrogen
CI complex I
CII complex II
CIII complex III
CIV complex IV
CV complex V
C5aR1 C5 substrate of the complement system receptor 1
CAT catalase
CBS cystathionine β-synthase
CD36 cluster of differentiation-36
CKD chronic kidney diseases
CoA coenzyme A
Cox I cytochrome c oxidase subunit 1
CPT I carnitine O-palmitoyl transferase I
CPT II carnitine O-palmitoyl transferase II
CPT IA CPT I isoform A
CPT IB CPT I isoform B
CSE cystathionine γ-lyase
Cu/Zn-SOD copper/zinc-SOD
Cys cysteine
CARSs cysteinyl-transfer RNA (tRNA) synthetases
Cyt c cytochrome c
DKD diabetic kidney disease
DN diabetic nephropathy
DNA deoxyribonucleic acid
Drp1 dynamin-related protein 1
DT distal tubules
EGFR epidermal growth factor receptor
EMT epithelial–mesenchymal transition
eNOS endothelial nitric oxide synthase
ERK2 extracellular regulated kinase 2
ERR estrogen and estrogen-related receptors
ETS electron transport system
FA fatty acids
FABP fatty-acid-binding protein
FADH2 flavin adenine dinucleotide
Fe2+ ferrous iron
Fe3+ ferric iron
Fe-S iron-sulfur
Fis1 fission protein 1
FoxO forkhead box O
GC4419 avasopasem manganese
GFRs growth factor receptors
GPx glutathione peroxidase
Grx glutaredoxin
GSH glutathione
GTPases guanosine triphosphatases
GST glutathione S-transferase
h hours
HK2 human proximal tubular cells
HS hydrosulfide radical.
H2O2 hydrogen peroxide
H2S gydrogen sulfide
His histidine
I/R ischemia/reperfusion
Idh2 isocitrate dehydrogenase isoform 2
IKKγ regulatory subunit of inhibitor IKK complex
IMM inner mitochondrial membrane
IMS intermembrane space
K2Cr2O7 potassium dichromate
L-NAME N(G)-nitro-L-arginine-methyl ester
LC3-II microtubule-associated protein 1A/1B-light chain 3 phosphatidylethanolamine conjugate
LDs lipid droplets
LOO lipid peroxyl radical
LPS lipopolysaccharides
Lys lysine
MA maleic acid
MAPK mitogen-activated protein kinases
MCAD medium-chain acetyl dehydrogenase
MDA malondialdehyde
Met methionine
MetO (R–SOCH3) methionine sulfoxide
MetO2 (RSO2CH3) methionine sulfone
Mff mitochondrial fission factor
Mfn1 mitofusin 1
Mfn2 mitofusin 2
Mief1 mitochondrial elongation factor 1
Mief2 mitochondrial elongation factor 2
mitoTEMPO 2-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl) triphenylphosphonium chloride
mitoQ mitochondrial-targeting antioxidants coenzyme Q
Mn-SOD manganese superoxide dismutase
mRNA messenger RNA
Msr methionine sulfoxide reductase
MsrA Msr isoform A
MPTP mitochondrial permeability transition pore
mt-KATP mitochondrial ATP-sensitive potassium K channel
mtDNA mitochondrial DNA
mtROS mitochondrial ROS
Na+/K+ ATPase sodium–potassium ATP pump
NAC N-acetylcysteine
NAD nicotinamide adenine dinucleotide
NADPH nicotinamide adenine dinucleotide phosphate
NaHS sodium hydrosulfide
NF-κB nuclear factor kappa-light-chain-enhancer of activated B cells
NOS nitric oxide synthase
NOXs NADPH oxidases
NRF-1 nuclear respiratory factor 1
NRF-2 nuclear respiratory factor 2
Nrf2 nuclear factor erythroid 2–related factor 2
O2 oxygen
O2•− superoxide anion radical
OA oxalacetate
OCR oxygen consumption rate
OMM outer mitochondrial membrane
ONOO peroxynitrite
Opa1 optical atrophy 1
OS oxidative stress
Ox-PTMs oxidative post-translational modifications
OXPHOS oxidative phosphorylation
p62 sequestosome
PDIA1 protein disulfide isomerase A1
PGC-1α peroxisome proliferator-activated receptor (PPAR) γ coactivator-1 alpha
Pink1 phosphatase and tensin homolog (PTEN)-induced putative kinase 1
PKC protein kinase C
PKC-ε PKC-epsilon
PKC-δ PKC-delta
PKM2 pyruvate kinase isoform M2
PMF proton motive force
PPARs peroxisome proliferator-activated receptor
Pro proline
Prx peroxiredoxin
PT proximal tubules
PTKs protein tyrosine kinases
PTM post-translational modifications
PTPs protein tyrosine phosphatases
R–S thyil radical
R–SNO S-nitrosothiol
R–SOH sulfenic acid
R–SO2H sulfinic acid
R–SO3H sulfonic acid
R–S(O)–S–R thiosulfinate
R–SN–R’ sulfenamide
R–S–S–H persulfonation
Rac1 Ras-related C3 botulinum toxin substrate 1
RAGE AGE receptor
ROS reactive oxygen species
RPTCs renal proximal tubular cells
RTC renal tubular cells
S thiolate anion
S–S disulfide bonds
SF sulforaphane
SH thiol
siRNA small interfering RNA
SIRT3 nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin-3
SN2 bimolecular nucleophilic substitution
SSG glutathionylation
TCA tricarboxylic acid
TECs tubular epithelial cells
TFAM transcription factor A
TGFβ1 transforming growth factor-beta 1
Thr threonine
Trx thioredoxin
Tyr tyrosine
UCPs uncoupling proteins
UCP1 uncoupling protein 1
UCP2 uncoupling protein 2
UCPs uncoupling proteins
UUO unilateral ureteral obstruction
VLCAD very long-chain acyl-CoA dehydrogenase
WT wild type