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Factors regulating M1/M2 microglia switching. Pro-inflammatory (Il-17, IFNγ, TNF-α) and anti-inflammatory (IL-4, IL-10, TGF-β) stimuli.
| M1 Neuroinflammation Induction |
M2 Homeostasis Mainteinance |
|---|---|
| IL-17 | IL-4 |
| IFNγ | IL-10 |
| TNF-α | TGF-β |
| Inflammatory cytochine production | anti-inflammatory molecule production |
