Table 2.
The effect of MA, AR on serum profiles in the experimental mice.
| Parameters | ND | HD | MA | AR | MA + AR |
|---|---|---|---|---|---|
| TC (mg/dL) | 111.2 ± 21.2 c | 192.4 ± 11.4 a | 184.7 ± 12.5 a | 178.4 ± 17.9 ab | 163.3 ± 22.2 b |
| TG (mg/dL) | 88.0 ± 13.6 b | 120.3 ± 20.7 a | 102.1 ± 13.5 b | 99.5 ± 10.6 b | 96.1 ± 11.6 b |
| HDL-C (mg/dL) | 47.5 ± 4.7 b | 56.8 ± 4.4 a | 60.5 ± 3.6 a | 59.3 ± 2.2 a | 60.4 ± 6.4 a |
| LDL-C (mg/dL) | 48.8 ± 20.7 c | 112.4 ± 14.6 a | 106.5 ± 10.3 ab | 99.4 ± 15.7 ab | 91.7 ± 13.6 b |
| VLDL (mg/dL) | 17.6 ± 2.7 b | 24.1 ± 4.1 a | 20.4 ± 2.7 b | 20.7 ± 3.1 b | 19.2 ± 2.3 b |
| Free fatty acid (nmol/μL) | 0.90 ± 0.01 ab | 0.99 ± 0.11 a | 0.71 ± 0.14 b | 0.75 ± 0.22 b | 0.74 ± 0.14 b |
| Glycerol (nmol/μL) | 0.22 ± 0.03 b | 0.28 ±0.03 a | 0.24 ± 20.02 b | 0.24 ± 0.03 b | 0.22 ± 0.03 b |
| Adiponectin (ng/mL) | 10.32 ± 0.30 a | 9.54 ±0.38 b | 11.05 ± 0.39 a | 10.51 ± 0.97 a | 10.50 ± 0.88 a |
| Leptin (ng/mL) | 4.15 ± 1.81 c | 75.24 ± 13.84 a | 61.19 ± 15.78 ab | 59.93 ± 9.51 ab | 56.08 ± 13.7 b |
| Insulin (ng/mL) | 0.06 ± 0.03 c | 1.44 ± 0.56 a | 0.66 ± 0.38 b | 0.71 ± 0.46 b | 0.98 ± 0.63 b |
M. alba extract (400 mg/kg bw), A. melanocarpa extract (400 mg/kg bw), or mixture of these two extracts was orally administered to experimental mice fed a high-fat diet for 14 weeks. TC, total cholesterol, TG, triglycerides, HDL-C, high-density lipoprotein cholesterol, LDL-C, low-density lipoprotein-cholesterol, VLDL, very low density-lipoprotein cholesterol. ND, normal diet, HD, high-fat diet, MA, high-fat diet + M. alba 400 mg/kg bw, AR, high-fat diet + A. melanocarpa 400 mg/kg bw, MA + AR, high-fat diet + mixture of M. alba and A. melanocarpa (400 mg/kg bw). Results are expressed as means ± S.D (n = 10). Means with different superscript letters (a, b, c) are significantly different from each other by Duncan’s test of ANOVA at p < 0.05. “a” denotes the highest value and “c” represents the lowest value.