Figure 1.

Morphological and karyotypic differences between sarcomas with simple and complex genomes. (A) schematic figure and HE staining demonstrating monomorphic nuclei. White arrows in simple karyotype image indicate a translocation (3:14), typically observed in translocation-driven sarcomas. (B) schematic figure and HE staining demonstrating polymorphic nuclei. The complex karyotype image displays extensive chromosomal aberrations, including chromosomal gains and translocations.