Table 3.
Case No | Diagnosis | Intra-Luminal Secretion | Two Most Dominant Patterns | Proportion of Architectural Patterns | Features Favor Endometrioid Carcinoma | Nuclear Atypia | TCN | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tub (%) | Duc (%) | Pap (%) | Solid (%) | CN-Like (%) | SC-Like (%) | AH/EIN | Squamous Metaplasia | Mucinous Metaplasia | Nuclear Pleomorphism | Conspicuous Nucleoli | Mitotic Count | |||||
1 | EC-MLD, grade 1 | Frequent | Duc, Tub | 25 | 70 | 5 | 0 | 0 | 0 | + | + | + | Mild to moderate | − | 2/10 HPFs | − |
2 | EC-MLD, grade 2 | Frequent | Duc, Tub | 20 | 70 | 0 | 10 | 0 | 0 | + | − | − | Moderate to severe | − | 21/10 HPFs | − |
3 | EC-MLD, grade 2 | Frequent | Tub, Duc | 50 | 35 | 0 | 10 | 0 | 5 | − | + | − | Mild to moderate | + | 14/10 HPFs | + |
4 | EC-MLD, grade 2 | Occasional | Pap, Tub | 25 | 20 | 45 | 10 | 0 | 0 | − | − | − | Moderate to severe | − | 24/10 HPFs | − |
5 | EC-MLD, grade 2 | Frequent | Duc, Tub | 35 | 60 | 0 | 10 | 5 | 0 | − | − | − | Moderate to severe | + | 25/10 HPFs | + |
Abbreviations: Tub, tubular; Duc, ductal; Pap, papillary; CN-like, comedonecrosis-like; SC-like, sex cord-like; AH/EIN, atypical hyperplasia/endometrioid intraepithelial neoplasia; TCN, tumor cell necrosis; EC-MLD, endometrioid carcinoma with mesonephric-like differentiation; HPFs, high-power fields.