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. 2021 Aug 11;11(8):1450. doi: 10.3390/diagnostics11081450

Table 3.

Pathological characteristics: detailed histological features.

Case No Diagnosis Intra-Luminal Secretion Two Most Dominant Patterns Proportion of Architectural Patterns Features Favor Endometrioid Carcinoma Nuclear Atypia TCN
Tub (%) Duc (%) Pap (%) Solid (%) CN-Like (%) SC-Like (%) AH/EIN Squamous Metaplasia Mucinous Metaplasia Nuclear Pleomorphism Conspicuous Nucleoli Mitotic Count
1 EC-MLD, grade 1 Frequent Duc, Tub 25 70 5 0 0 0 + + + Mild to moderate 2/10 HPFs
2 EC-MLD, grade 2 Frequent Duc, Tub 20 70 0 10 0 0 + Moderate to severe 21/10 HPFs
3 EC-MLD, grade 2 Frequent Tub, Duc 50 35 0 10 0 5 + Mild to moderate + 14/10 HPFs +
4 EC-MLD, grade 2 Occasional Pap, Tub 25 20 45 10 0 0 Moderate to severe 24/10 HPFs
5 EC-MLD, grade 2 Frequent Duc, Tub 35 60 0 10 5 0 Moderate to severe + 25/10 HPFs +

Abbreviations: Tub, tubular; Duc, ductal; Pap, papillary; CN-like, comedonecrosis-like; SC-like, sex cord-like; AH/EIN, atypical hyperplasia/endometrioid intraepithelial neoplasia; TCN, tumor cell necrosis; EC-MLD, endometrioid carcinoma with mesonephric-like differentiation; HPFs, high-power fields.