Table 2.
Studies | Lesion Size (mm) | Peripheral Distribution | Bronchus Sign Present | Distance to Pleura | Diagnostic Sensitivity |
---|---|---|---|---|---|
MonarchTM | |||||
Cadaveric | |||||
Chen [23] (n = 67) |
20.4 (9.6–28.3) | 100% < 3 cm from pleura | NS | 16 ± 10.6 mm (mean) | 65/67 (97%) |
Human | |||||
Rojas-Solano [24] (n = 15) |
26.0 (10–63) | 80% | 100% | 6 (0–34) mm (range) | 14/15 (93%) * |
Chaddha [25] (n = 165) |
25.0 ± 15.0 | 71% | 63.5% | NS | 114–127/165 (69.1–77%) # |
Chen [26] (n = 54) |
23.2 ± 10.8 | 100% | 59.3% | NS | 40/54 (74.1%) |
IonTM | |||||
Cadaveric | |||||
Yarmus [27] (n = 20) |
16.5 ± 1.5 | 80% | 50% | NS | 16/20 (80%) |
Human | |||||
Fielding [28] (n = 29) |
15.3 ± 4.8 | 100% | 58.6% | >15 mm for all lesions | 23/29 (79.3%) |
Bajwa [29] (n = 76) |
17.0 (6–70) | NS | NS | NS | 70/76 (92%) ¥ |
n = number of lesions biopsied (except Chaddha [25] and Bajwa [29], where n = number of cases); NS = not specified; peripheral distribution = lesion in outer 1/3 of lung, or inaccessible using white-light and convex probe EBUS bronchoscope (Chen [23]). * Study did not report diagnostic sensitivity, but 14/15 lesions had diagnostic sampling. # Assuming the biopsy-proven inflammation (n = 13) was nondiagnostic vs. diagnostic. ¥ This is an ATS abstract.