Figure 1.

Distribution of focal IF/TA and diffuse fibrosis in experimental kidney diseases with different types of injury. (A) Representative photomicrograph of Masson’s trichrome-stained kidney section in mouse models of experimental kidney diseases (scale bars: 200 μm). (B) The scatter dot plots represent medians with individual data points summarizing the extent of total kidney fibrosis in indicated experimental models (n = 5 mice in each group). (C) The bar graph represents the fraction of focal IF/TA and diffuse fibrosis relative to total fibrosis in the indicated experimental models (n = 5 mice in each group). Abbreviations: FAN—folic acid-induced nephropathy; IF/TA—interstitial fibrosis/tubular atrophy; NTN—nephrotoxic serum-nephritis; UUO—unilateral ureteral obstruction.