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. 2021 Aug 9;10(8):2035. doi: 10.3390/cells10082035

Figure 5.

Figure 5

Long-term hepatic expression of IRA improves lipid depot in aortic roots: (A) representative microphotographs of Oil Red O/hematoxylin staining in aortic root sections from control (n = 3), iLIRKO (n = 3), iLIRKO IRA (n = 3), iLIRKO IRB (n = 3). As a reference, we used sections of aortic root from ApoE−/− mice under 8 weeks (n = 3) and 24 weeks (n = 5) of Western diet. Quantifications of lipid depot (B) and lesion area (C) in aortic roots from the six groups studied. Results are expressed as mean ± SEM. The statistical significance was represented as * (p < 0.05), ** (p < 0.01), **** (p < 0.0001) vs. control mice.