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Bone sarcoma stem cells overview. (a) osteosarcoma; (b) Ewing sarcoma; (c) chondrosarcoma. (d) A broad spectrum of CSC markers (black) and the molecular mechanisms underlying CSC phenotypes (blue) have been documented for each sarcoma. Several anti-CSC compounds (red) have been preclinically tried to inhibit CSC phenotypes. Reprinted from an open-access source [20].
