Skip to main content
. 2021 Jul 22;11(8):1315. doi: 10.3390/diagnostics11081315

Figure 6.

Figure 6

Sensitivity and specificity values using different SK index threshold parameters and receiver operating characteristic (ROC) curves for melanoma prediction. Melanoma (MM) group compared to SK group (a) and MM-like SK group compared to SK-like MM (b). We used different thresholds of the SK index and 30 proved to be the most suitable for a screening device, where the sensitivity is 91.9% (over 90%) and specificity is 57.0% (over 50%). Setting the right threshold was important from the aspect of the sensitivity and specificity for a potential screening tool. The 30 threshold was suitable with a sensitivity of 83.3% and specificity of 51.9% for a potential screening device. ROC was performed to show the differences between the comparison of the MM and SK (c) and MM-like SK and SK-like MM groups (d). The Area Under the Curve (AUC) was 0.844 (patients: MM, control: SK, 95% confidence interval, p < 0,0001) in the MM and SK ROC curve (c). AUC was 0.826 (patients: SK-like MM, control: MM-like SK, 95% confidence interval, p = 0.0092) in ROC curve of the MM-like SK and SK-like MM comparison. Y-axis: sensitivity, x-axis: 1-specificity. Red diagonal dotted line represents a non-discriminatory test (c,d).