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. 2021 Jul 26;11(8):1101. doi: 10.3390/biom11081101

Table 3.

LRRK2 GTPase inhibitors developed to date.

Compound Name Chemical Structure Brain Permeability Reference
68 graphic file with name biomolecules-11-01101-i009.jpg yes [72]
70 graphic file with name biomolecules-11-01101-i010.jpg n.a. [72]
FX2149 graphic file with name biomolecules-11-01101-i011.jpg yes [109]

n.a.—not available (compound insoluble).