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. 2021 Jul 31;9(8):928. doi: 10.3390/biomedicines9080928

Figure 2.

Figure 2

DNA target biosensor using nanomaterial-based FRET. (a) Schematic representation of the detection of a deletion mutation in exon 19 of the EFGR gene on a graphene oxide surface [68]. (b) Schematic diagram of the FRET-based RGB detection of DNA as a cancer biomarker by using a smartphone. This figure is reproduced from [64] (© 2016 Elsevier B.V.); Green emission from the nanoprobe (NP) surface transfers some of the excitation energy to the FRET receptor on the NP surface and, thereby, causes the NP to fluoresce in yellow–orange. (c) Smartphone-based data analysis. Green and red RGB images are taken, and intensity ratios between the channels are evaluated. This figure is reproduced from [66] (© 2020 Elsevier B.V.).