Table 3.
Multivariable analysis testing of MTV, ECOG with maximal standardized distances (SDmax) calculated with each method for PFS and OS prediction. Boldface p-values are significant at p < 0.05.
| Factors | Multivariate Analysis of PFS | Multivariate Analysis of OS | ||
|---|---|---|---|---|
| HR (95% CI) | p | HR (95% CI) | p | |
| High SDmax_Euc | 2.4 (1.5–4.0) | 0.0004 | 1.8 (0.98–3.4) | 0.0586 |
| MTV > 220 cm3 | 2.1 (1.3–3.3) | 0.0027 | 3.1 (1.6–6.0) | 0.0012 |
| ECOG 2–3 | 2.3 (1.4–3.8) | 0.0007 | 2.3 (1.3–4.0) | 0.0062 |
| HighSDmax_Man | 2.1 (1.3–3.4) | 0.0022 | 1.7 (0.91–3.0) | 0.0971 |
| MTV > 220 cm3 | 2.0 (1.2–3.2) | 0.0052 | 3.0 (1.5–6.0) | 0.0015 |
| ECOG 2–3 | 2.3 (1.4–3.7) | 0.0011 | 2.2 (1.2–4.0) | 0.0076 |
| High SDmax_Tch | 2.4 (1.5–3.9) | 0.0004 | 1.9 (1.0–3.4) | 0.0433 |
| MTV > 220 cm3 | 2.0 (1.2–3.2) | 0.0064 | 3.0 (1.5–5.8) | 0.0018 |
| ECOG 2–3 | 2.2 (1.4–3.6) | 0.0013 | 2.2 (1.2–4.0) | 0.0076 |
| High SD_TSP | 2.2 (1.2–3.9) | 0.0084 | 1.9 (0.93–3.8) | 0.081 |
| MTV > 220 cm3 | 2.0 (1.2–3.2) | 0.0055 | 3.0 (1.5–5.9) | 0.0018 |
| ECOG 2–3 | 2.4 (1.5–3.9) | 0.0005 | 2.4 (1.3–4.2) | 0.0038 |
| High SDmax_Euc _Vox | 2.7 (1.6–4.6) | 0.0001 | 2.0 (1.0–3.7) | 0.0389 |
| MTV > 220 cm3 | 2.0 (1.2–3.2) | 0.0051 | 3.0 (1.5–5.9) | 0.0014 |
| ECOG 2–3 | 2.3 (1.4–3.7) | 0.001 | 2.2 (1.2–4.0) | 0.0073 |
| High SDmax_Man_Vox | 2.3 (1.4–3.7) | 0.0006 | 1.9 (1.1–3.5) | 0.0306 |
| MTV > 220 cm3 | 2.0 (1.3–3.2) | 0.0038 | 3.0 (1.5–5.9) | 0.0013 |
| ECOG 2–3 | 2.3 (1.4–3.8) | 0.0006 | 2.2 (1.2–4.0) | 0.0068 |
| High SDmax_Tch_Vox | 2.8 (1.6–4.7) | 0.0002 | 1.8 (0.91–3.6) | 0.0911 |
| MTV > 220 cm3 | 2.0 (1.2–3.2) | 0.0048 | 3.1 (1.6–6.0) | 0.0012 |
| ECOG 2–3 | 2.2 (1.4–3.6) | 0.0012 | 2.2 (1.2–4.0) | 0.0075 |