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. 2021 Aug 8;22(4):1139. doi: 10.3892/etm.2021.10573

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Copyright: © Huang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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CTRP9 overexpression alleviates inflammation after H/R damage. ELISA was performed to measure (A) TNF-α, (B) IL-6 and (C) IL-10 levels. TNF-α and IL-6 levels were markedly increased after H/R damage, but IL-10 levels decreased. CTRP9 overexpression reduced TNF-α and IL-6 levels but increased IL-10 levels. Data are presented as the mean ± SD (n=6). ^*P<0.05 vs. control. ^#P<0.05 vs. H/R or Ad-GFP. CTRP9, C1q/TNF-related protein 9; H/R, hypoxia/reoxygenation; Ad-GFP, adenovirus encoding green fluorescent protein.