Skip to main content
. 2021 Jul 31;10(8):1948. doi: 10.3390/cells10081948

Figure 1.

Figure 1

Schematic representation of a 2′-O-methylated ribose (A) and a C/D box snoRNP (also named the methylation complex) (B) The C/D box snoRNP includes the methyltransferase protein Fibrillarin (light yellow), NOP56 (purple), NOP58 (light brown), NHP2L1 (light blue), and the C/D snoRNA (light orange). Boxes C/C’ (orange) and D/D’ (red) are shown. The rRNA forms an RNA:RNA duplex with the C/D snoRNA. The FBL catalytic domain 2′O-methylates the fifth nucleotide downstream the boxes D or D’ and indicated by a blue star.