Table 3.
Comparison of ALS case and age-matched control characteristics.
| Characteristic | Control (n = 6) |
ALS (n = 9) |
p Value |
|---|---|---|---|
| Age at death, years | 62.05 (8.8) | 66.32 (6.94) | 0.313 |
| Male | 4 (66%) | 6 (66%) | 0.706 1 |
| PMI, hours | 33.25 (18.4) | 18.66 (12.31) | 0.087 |
| Y1R density (µm)3 × L5 Soma | 0.24 (0.04) | 0.29 (0.04) | 0.077 |
| Y1R density (µm)3 × *L4/5 Dendrite | 0.31 (0.08) | 0.32 (0.13) | 0.915 |
| Y1R density (µm)3 × *L2/3 Dendrite | 0.44 (0.07) | 0.38 (0.05) | 0.194 |
Continuous variables are expressed as the mean ± (SD) and categorical variables are expressed as n (%). p values are based on 1 Fisher’s exact test (sex), other ANOVA (age at death, PMI and Y1R density). Abbreviations: PMI = post-mortem interval; Y1R = neuropeptide Y1 receptor * dendrite analyses utilized n = 3 controls and n = 5 ALS cases.