Table 2.
Post-mortem tissue donor demographics
| Group | Case code | Age (y) | Sex | Post-mortem delay (h) | Cause of death |
|---|---|---|---|---|---|
| Control (n = 5) | H232 | 89 | F | 28.5 | Multiple stroke, dementia |
| H233 | 83 | F | 18 | Acute renal failure, bowel cancer | |
| H234 | 86 | M | 3 | Stroke, dementia | |
| H235 | 83 | M | 21 | Hypothermia | |
| H236 | 96 | F | 15 | General inanition | |
| Mean (± SD) | 87.4 ± 5.4 | F/M: 3/2 | 17.1 ± 9.3 |
| Group | Case code | Age (y) | Sex | Post-mortem delay (h) | sALS/fALS (genotype) | Site of onset |
|---|---|---|---|---|---|---|
| ALS (n = 13) | MN7 | 55 | F | 56 | sALS | Upper limb |
| MN10 | 46 | M | 24 | sALS | Lower limb | |
| MN11 | 77 | F | 18 | fALS | Lower limb | |
| MN12 | 49 | M | 34 | sALS | Respiratory | |
| MN13 | 55 | M | 10 | sALS | Upper limb | |
| MN14 | 59 | F | 19 | fALS | Bulbar | |
| MN15 | 54 | F | 18 | sALS | FTD | |
| MN16 | 69 | M | 16.5 | sALS | Upper limb | |
| MN18 | 53 | F | 12 | fALS (C9ORF72) | Lower limb | |
| MN20 | 85 | M | 15 | sALS | Lower limb | |
| MN21 | 59 | F | 17.5 | fALS | Lower limb | |
| MN22 | 64 | F | 9 | sALS | Upper limb | |
| MN23 | 79 | F | 27 | fALS (C9ORF72) | Lower limb | |
| Mean (± SD) | 61.8 ± 12.2 | F/M: 8/5 | 21.2 ± 12.5 |
sALS sporadic ALS, fALS familial ALS, FTD frontotemporal dementia