Figure 4.

Inhibition of intestinal α-glucosidase by N. sativa seed (a) hexane extract (EH) and resulting fractions (SH1–SH8) and (b) acetone extract (AE) and resulting fractions (SA1–SA11) at two doses (166 and 332 µg/mL). The drug acarbose was used as a positive control at 50 µM (3.22 µg/mL) and resulted in 89.2 ± 0.5% inhibition. Extraction solvent was used as negative control (blank) and was subtracted to each corresponding extract or fraction inhibition value. Data are mean values ± standard deviation of 3 independent experiments.