Table 1.
SARS-CoV-2 variants with amino acid substitutions on RBD.
| WHO label | Pango lineage | RBD substitutions | Earliest documented samples |
|---|---|---|---|
| Alpha | B.1.1.7 | N501Y | United Kingdom, Sep-2020 |
| Beta | B.1.351 | K417N E484K N501Y | South Africa, May-2020 |
| Gamma | P.1 | K417T E484K N501Y | Brazil, Nov-2020 |
| Delta | B.1.617.2 | L452R T478K | India, Oct-2020 |
| Eta | B.1.525 | E484K | Multiple countries, Dec-2020 |
| Lota | B.1.526 | E484K | United States of America, Nov-2020 |
| Kappa | B.1.617.1 | L452R E484Q | India, Oct-2020 |
| Lambda | C.37 | L452Q F490S | Peru, Dec-2020 |