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. 2021 Aug 27;231:108842. doi: 10.1016/j.clim.2021.108842

Table 2.

List of drugs with general, IUPAC names, PubChem IDs with mechanism.

S. No. Drug general name IUPAC name PubChem ID Mechanism Reference
1. Remdesivir 2-ethylbutyl (2S)-2-[[[(2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxyoxolan-2-yl]methoxy-phenoxyphosphoryl]amino]propanoate 121304016 Inhibition of RNA Polymerase [170]
2. Baricitinib 2-[1-ethylsulfonyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]azetidin-3-yl]acetonitrile 44205240 Inhibition of Janus Kinase 1 and 2 [175]
3. Ruxolitinib (3R)-3-cyclopentyl-3-[4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrazol-1-yl]propanenitrile 25126798 Inhibition of Janus Kinase [176]
4. Nafamostat mesylate (6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate;methanesulfonic acid 5311180 Inhibitor of TMPRSS2 [178]
5. Camostat mesylate [4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate;methanesulfonic acid 5284360 Inhibitor of TMPRSS2 [178]
6. Warfarin 4-hydroxy-3(3-oxo-1-phenylbutyl)-2H-chromen-2-one 54678486 Inhibition of blood clots [180]
7. Aspirin 2-acetyloxybenzoic acid 2244 Inhibition of initiation of inflammatory reactions and blood clots [181]