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Schematic structure of STAT3 protein: STAT3 has a N-terminus domain (NTD), a coil-coiled domain (CDD), a DNA binding domain (DBD), a linker region (LD), a SH2 domain, and a transactivation domain (TAD) in the C-terminal portion of the protein. Phosphorylation, acetylation, and methylation sites are highlighted. Created with BioRender.com.
