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. 2021 Aug 20;18(16):8790. doi: 10.3390/ijerph18168790

Table 5.

Associated factors of scores of depression, anxiety and insomnia symptoms during the course of COVID-19 in the multivariable generalized linear mixed models a.

Factors Depression Anxiety Insomnia
b (SE) p-Value b (SE) p-Value b (SE) p-Value
Gender: male (vs. female) 0.37 (0.08) <0.001 0.06 (0.07) 0.39 0.34 (0.09) <0.001
Age (years) −0.02 (0.01) <0.001 −0.01 (0.00) 0.007 0.01 (0.01) 0.15
Marital status: married (vs unmarried) −0.38 (0.11) <0.001 −0.02 (0.09) 0.82 −0.70 (0.12) <0.001
Family members of COVID-19 patients: yes (vs. no) 1.48 (0.30) <0.001 1.44 (0.25) <0.001 1.99 (0.31) <0.001
Experiences of quarantine: yes (vs. no) 0.74 (0.08) <0.001 0.64 (0.07) <0.001 0.58 (0.09) <0.001
Living in province most severely affected by initial peak: yes (vs. no) 0.81 (0.18) <0.001 1.04 (0.16) <0.001 0.71 (0.20) <0.001
Self-perceived occupational exposure risk to COVID-19: yes (vs. no) 0.87 (0.12) <0.001 0.70 (0.10) <0.001 0.38 (0.13) 0.003
Living in places with COVID-19 resurgences: yes (vs. no) 0.69 (0.10) <0.001 0.45 (0.09) <0.001 0.83 (0.11) <0.001
Increases in work burden after resuming work: yes (vs. no) 1.07 (0.08) <0.001 1.02 (0.07) <0.001 1.27 (0.09) <0.001
Wearing face masks voluntarily when going out: yes (vs. no) −0.93 (0.23) <0.001 −0.56 (0.20) 0.004 −0.72 (0.24) 0.003
Reducing social gatherings voluntarily: yes (vs. no) −0.51 (0.14) <0.001 −0.15 (0.12) 0.21 −0.22 (0.15) 0.14
Seeking psychological consultation since COVID-19: yes (vs. no) 2.72 (0.12) <0.001 2.03 (0.11) <0.001 1.82 (0.13) <0.001
Educational level × time: college school or higher (vs. lower than college school) 0.02 (0.01) 0.03 0.03 (0.01) 0.003 0.05 (0.01) 0.001
Living in places with COVID-19 resurgences × time: yes (vs. no) 0.03 (0.01) 0.003 0.04 (0.01) 0.002 0.03 (0.02) 0.10
Increases in work burden after resuming work × time: yes (vs. no) 0.04 (0.01) <0.001 0.02 (0.01) 0.04 0.09 (0.01) <0.001
Wearing face masks voluntarily when going out × time: yes (vs. no) −0.07 (0.03) 0.005 −0.07 (0.03) 0.02 −0.05 (0.04) 0.17
Reducing social gatherings voluntarily × time: yes (vs. no) −0.02 (0.01) 0.15 −0.05 (0.02) 0.003 −0.08 (0.02) <0.001
Seeking psychological consultation since COVID-19 × time: yes (vs. no) 0.21 (0.02) <0.001 0.19 (0.02) <0.001 0.21 (0.02) <0.001

a Values were from multivariable generalized linear mixed models with random within-subject intercepts and autoregressive covariance structures. The multivariable models included fixed effects for time (coded as 0 at baseline, and 5 at follow-up), as well as all factors and their interaction terms with time that showed significance in their individual univariable generalized linear mixed models.