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. 2021 Aug 20;9(8):1053. doi: 10.3390/biomedicines9081053

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Assessment of kidney and left ventricle tissue availability of biologically active products of cytochrome P-450-dependent epoxygenase pathway of arachidonic acid metabolism. Kidney (A) and left ventricle (B) ratio in epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acids (DHETEs) in sham-operated transgene-negative Hannover Sprague-Dawley rats (HanSD), sham-operated heterozygous Ren-2 transgenic rats (TGR), and TGR rats with aorto-caval fistula (ACF) two weeks after creation of ACF or sham-operation. * p < 0.05 versus sham-operated HanSD rats and sham-operated TGR.