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. 2021 Aug 26;13:165. doi: 10.1186/s13148-021-01153-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 3 — Boxplot of placental DNAm and gene expression levels. The x-axis denotes placental DNAm of cg22363520, based on median split (beta-value of 0.9522), beta-values below or equal to the median are depicted in purple, beta-values above the median depicted in yellow. The y-axis denotes gene expression levels of FKBP5 after variance-stabilizing transformation. The association stays significant after exclusion of one potential outlier in the group below the median (p = 0.0036) (a). The x-axis denotes placental DNAm of cg22363520, based on median split (beta-value of 0.9522), beta-values below or equal to the median are depicted in purple, beta-values above the median depicted in yellow. The y-axis denotes the eigengene of the turquoise module (b)