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Profiling of genetic mutations and MICs for LZD-resistant MTB isolates
| Locus | Mutation | No. of isolates with corresponding MIC (μg/ml) | Total (%) | |||
|---|---|---|---|---|---|---|
| 2 | 4 | 8 | > 8 | |||
| rplC | Cys154Arg | 5 | 5 | 2 | 12 (40.0) | |
| 23S rRNA | G2270C | 1 | 1 (3.3) | |||
| G2270T | 2 | 1 | 3 (10.0) | |||
| Wild-type | 7 | 6 | 1 | 14 (46.7) | ||
| Total | 7 | 14 | 7 | 2 | 30 (100.0) | |
MIC, minimum inhibitory concentration; LZD, linezolid; MTB, Mycobacterium tuberculosis
