Table 2.
Results of the studied TDP-43 ATCG sequences.
| TDP-43 Protein Sequences | Fractal Dimension ATCG | ATCG Di-Nucleotide Entropy (4 Bits Max) |
ATCG Mono-Nucleotide Entropy (2 Bits Max) |
Correlation Coefficient |
Annotations |
|---|---|---|---|---|---|
| 266 aa (1–266) | 1.9939 | 3.9278 | 1.9812 | 0.9931 (FD and di-nucleotide entropy) |
Non-LCD |
| 148 aa (267–414) | 1.9757 | 3.8367 | 1.9665 | 0.9970 (FD and mono-nucleotide entropy) |
LCD inside TDP-43 |
| 414 aa | 1.9892 | 3.9146 | 1.9785 | entire TDP-43 | |
| 68 aa (276–343) | 1.9652 | 3.7538 | 1.9378 | 0.9233 (FD and di-nucleotide entropy) |
cryo-EM N-terminal of LCD |
| 71 aa (344–414) | 1.9833 | 3.8528 | 1.9896 | 0.9731 (FD and mono-nucleotide entropy) |
cryo-EM Remaining LCD |
| 139 aa (276–414) | 1.9731 | 3.8318 | 1.9709 | cryo-EM LCD |