Table 6.
Clinical trials on tumor suppressor gene therapies for high-grade gliomas.
| # | ClinicalTrials.gov Identifier | Title | Status | Phase | Diseases | # of Pts. Enrolled | Treatment | Locations |
|---|---|---|---|---|---|---|---|---|
| 1 | NCT00004041 | Gene Therapy in Treating Patients with Recurrent Malignant Gliomas |
Completed | I | Brain and Central Nervous System Tumors | NA | Biological: Ad5CMV-p53 gene; Procedure: conventional surgery | USA |
| 2 | NCT00004080 | Gene Therapy in Treating Patients with Recurrent or Progressive Brain Tumors |
Completed | I | Brain and Central Nervous System Tumors | NA | Biological: recombinant adenovirus-p53 SCH-58500; Procedure: conventional surgery | NA |
Ad: Adenovirus; CMV: Citomegalovirus; NA: Not Available; Pts: Patients; USA: United States of America.