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. 2021 Jul 31;10(8):1954. doi: 10.3390/cells10081954

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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PLA attenuates adipose tissue browning in Ctns^−/− mice. Gene expression of beige adipocyte markers (CD137, Tb-1 and Tmem26) in inguinal WAT was measured by qPCR. Gene expression of the Cox2 signaling pathway and toll like receptor pathway (Cox2, Pgf2α, Tlr2, Myd88 and Traf6) in inguinal WAT was also measured. Final results were expressed in arbitrary units, with one unit being the mean level in vehicle-treated WT mice. In addition, results of PLA-treated Ctns^−/− mice were compared to vehicle-treated Ctns^−/− mice and specific p-values are shown above the bar. ns signifies not significant, *** p < 0.001.