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. 2021 Aug 26;19:369. doi: 10.1186/s12967-021-03046-3

Table 2.

Comparison of laboratory index

Group Counts Mean±SD Median (0.25-0.75) Median (0.025–0.975) Min Max CV P
AGE (years)
 Benign mass 19 34.474±10.808 30 (27–41.5) 30 (18.05–52.4) 14 56 31.35% 0.001**
 Malignancy mass 44 48.25±13.404 51.5 (39–56.25) 51.5 (21.075–70.85) 18 73 27.78%
 Total 63 44.095±14.112 46 (35–55) 46 (19.65–69.9) 14 73 32.00%
CA125 (U/ml)
 Benign mass 19 83.387±112.353 24.89 (13.765–78.24) 24.89 (7.425–336.055) 6.98 390.1 134.74% 0.001**
 Malignancy mass 44 560.282±854.994 214.7 (65.523–428.975) 214.7 (8.025–2986.7) 6.98 3190.6 152.60%
 Total 63 416.457±747.887 86.62 (25.445–318.2) 86.62 (7.524–2756.8) 6.98 3190.6 179.58%
HE4 (U/ml)
 Benign mass 19 63.595±51.849 45.49 (40.175–53.49) 45.49 (34.13–199.065) 31.7 251.4 81.53% 0.000**
 Malignancy mass 44 286.382±534.32 128.55 (60.925–220.55) 128.55 (45.6–1458.577) 45.49 3235.9 186.58%
 Total 63 219.192±457.614 67.8 (46.71–167.65) 67.8 (38.206–1196.235) 31.7 3235.9 208.77%
ROMA
 Benign mass 19 0.189±0.278 0.06 (0.045–0.13) 0.06 (0.034–0.905) 0.03 0.99 147.09% 0.000**
 Malignancy mass 44 0.683±0.387 0.96 (0.277–1) 0.96 (0.06–1) 0.06 1 56.66%
 Total 63 0.534±0.422 0.52 (0.075–1) 0.52 (0.04–1) 0.03 1 79.03%
CNV
 Benign mass 19 2.579±1.805 2 (1.5–3.5) 2 (0–6.1) 0 7 69.99% 0.000**
 Malignancy mass 44 14.432±27.812 5 (3–11.5) 5 (0–69.575) 0 168 192.71%
 Total 63 10.857±23.822 4 (2–8.5) 4 (0–60.55) 0 168 219.42%
Zmax
 Benign mass 19 4.937±2.6 5.06 (3.445–6.36) 5.06 (0–9.623) 0 11.22 52.66% 0.021*
 Malignancy mass 44 10.421±11.091 6.05 (4.672–10.973) 6.05 (0–47.258) 0 52.77 106.43%
 Total 63 8.767±9.681 5.66 (4.455–9.745) 5.66 (0–39.833) 0 52.77 110.43%
Zmean
 Benign mass 19 3.676±1.499 3.83 (3.305–4.305) 3.83 (0–5.429) 0 5.51 40.78% 0.005**
 Malignancy mass 44 5.059±2.536 4.77 (4.245–5.66) 4.77 (0–12.228) 0 12.53 50.13%
 Total 63 4.642±2.35 4.46 (3.69–5.265) 4.46 (0–11.71) 0 12.53 50.62%
RM
 Benign mass 19 0.879±2.304 0.32 (− 0.04-0.84) 0.32 (− 0.683–6.699) − 0.71 9.79 262.12% 0.000**
 Malignancy mass 44 63.872±216.976 4.73 (1.532–16.795) 4.73 (− 0.139–608.251) − 0.15 1289.65 339.70%
Total 63 44.874±183.035 2.39 (0.185–10.185) 2.39 (− 0.502–468.421) − 0.71 1289.65 407.89%
Benign mass (N = 19) Malignancy mass (N = 44) Total (N = 63) P
Marriage
 Yes 16 (84.2%) 40 (90.9%) 56 (88.9%) 0.115 0.734
 No 3 (15.8%) 4 (9.1%) 7 (11.1%)
Childbirth
 Yes 14 (73.7%) 40 (90.9%) 54 (85.7%) 1.962 0.161
 No 5 (26.3%) 4 (9.1%) 9 (14.3%)
Menopausal status
 PreMenopausal 18 (94.7%) 22 (50.0%) 40 (63.5%) 11.457 0.001**
 PostMenopausal 1 (5.3%) 22 (50.0%) 23 (36.5%)

*p<0.05, **p<0.01