Table 4.
Association of DUSP6 SNPs and risk of surgical NEC
| SNP-rs | Minor Allele Allele |
Calculated medical NEC MAF (n = 30) |
Calculated surgical NEC MAF (n = 20) |
OR (95% CI) |
p-value |
|---|---|---|---|---|---|
| rs704074 | G | 0.27 | 0.08 | 0.21 (0.05, 0.84) | 0.012* |
| rs704073 | T | 0.27 | 0.07 | 0.14 (0.03, 0.68) | 0.003* |
| rs10744 | T | 0.27 | 0.07 | 0.14 (0.03, 0.68) | 0.003* |
Abbreviations: DUSP = Dual Specificity Phosphatase; NEC = necrotizing enterocolitis; SNP = single nucleotide polymorphism; MAF = minor allele frequency.
p-value obtained by logistic regression.