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Gene expression of IL-8 gene. ciPTECs were treated with PN149 or cisplatin (10, 20, 50 µM), carboplatin (100, 200, 500 µM) or oxaliplatin (20, 50, 100 and 150 µM) for 24 h. Gene expression was determined by high-throughput RT-qPCR. Shown are the log2 mean values of three independent experiments normalized to the untreated control, whereby the control equals 0.
