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. 2021 Aug 15;12(8):1200–1219. doi: 10.4239/wjd.v12.i8.1200

Table 1.

Genetic variants associated with macrovascular complications of type 2 diabetes mellitus


Gene symbol
Region
dbSNP ID
Risk allele
Condition
Ref.
1 GLUL 1q25 rs10911021 C CAD Qi et al[18], Beaney et al[19], and Look AHEAD Research Group[20]
2 MGMT 10q26.3 rs9299870 A Cardiovascular mortality Shah et al[23]
3 Intergenic 5q13 rs57922 T Cardiovascular mortality Shah et al[23]
4 CDKN2B-AS1 9p21 rs10757274 G MI Doria et al[11], and Zhang et al[17]
5 CDKN2B-AS1 9p21 rs2383206 G MI Doria et al[11], and Zhang et al[17]
6 CDKN2B-AS1 9p21 rs4977574 G CAD Qi et al[12]
7 PHACTR1 6p24 rs12526453 C CAD Qi et al[12]
8 CELSR2 1p21 rs646776 T CAD Qi et al[12]
9 HNF1A 12q24 rs2259816 T CAD Qi et al[12]
10 PCSK9 1p32 rs11206510 T CAD Qi et al[12]
11 LPA 6q25 rs74617384 T CAD Fall et al[24]
12 CDKN2B-AS1 9p21 rs10811652 C CAD Fall et al[24]

CAD: Coronary artery disease; MI: Myocardial infarction.