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. 2021 Jul 27;11(8):1106. doi: 10.3390/biom11081106

Table 5.

MIC values of NE-incubated next generation peptides and parents against P. aeruginosa 27853 following NE incubation. MIC values of NE-incubated peptides against P. aeruginosa 27853 as determined by RDAs. Peptides were incubated with/without 500 nM NE for four hours prior to RDAs.

Peptide MIC (μM ± SEM) against P. aeruginosa 27853
Peptide Alone Peptide + NE Fold Change in MIC
Sn1b (n = 4) 3.59 ± 2.13 7.31 ± 3.36 2.04
Sn1bN (n = 2) 5.32 ± 4.16 5.09 ± 4.31 0.957
SnE1 (n = 4) 3.25 ± 1.96 5.07 ± 3.85 1.56
SnE1N (n = 3) 4.28 ± 2.03 6.54 ± 3.87 1.53
SnE1-F (n = 2) 2.04 ± 0.315 4.84 ± 1.31 2.37