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. 2021 Aug 15;18(16):8615. doi: 10.3390/ijerph18168615

Table 2.

Distribution of up- and down-regulated genes in KEGG pathways.

KEGG Pathways (Level 2) MB2 vs. CMA MB4 vs. CMA
Up Down Up Down
Amino acid metabolism 42 25 39 38
Carbohydrate metabolism 59 40 52 60
Energy metabolism 31 44 27 52
Metabolism of cofactors and vitamins 33 15 28 23
Lipid metabolism 15 6 16 11
Translation 16 3 14 2
Metabolism of other amino acids 9 4 9 4
Biosynthesis of other secondary metabolites 7 4 9 5
Nucleotide metabolism 12 11 7 15
Metabolism of terpenoids and polyketides 8 7 7 4
Replication and repair 6 10 5 14
Membrane transport 4 8 2 9
Xenobiotics biodegradation and metabolism 5 2 3 3
Transcription 2 1 2 1
Signal transduction 1 4 1 3
Immune system 0 2 0 2
Glycan biosynthesis and metabolism 2 2 1 4
Folding, sorting and degradation 8 3 5 8
Cell growth and death 1 1 1 1
Cellular community—prokaryotes 1 7 1 8
Environmental adaptation - - 0 1