Figure 1.

General experimental design for studying the effects of arginine supplementation on ECM secretion and expression by human corneal fibroblasts. The initial step was human corneal tissue collection, corneal fibroblast expansion, and construction of 3D corneal stromal models followed by arginine supplementation. Comparisons between healthy (HCF) and KC-derived (HKC) constructs were performed. Pictorials modified from Servier Medical Art under a Creative Commons Attribution 3.0 Unported License.