. 2021 Jul 21;11(8):1310. doi: 10.3390/diagnostics11081310

Table 1.

Results of the survey regarding brain and spine MRI at baseline.

BASELINE
BRAIN MRI
MRI SEQUENCES	Number of Affirmative Answers	Percentage	Additional Questions		Number of Answers	Percentage
*T1-weighted*
2D SE-T1w (pre-Gd)	30	65.2%	slice thickness	≤3 mm	8	26.7%
			slice thickness	>3 mm	22	73.3%
			gap	Yes	10	33.3%
			gap	No	20	66.7%
3D SE-T1w (pre-Gd)	6	13.0%	voxel size	<1 mm (isotropic)	3	50.0%
				1 mm (isotropic)	3	50.0%
				other	0	0.0%
3D GrE-T1w (pre-Gd)	13	28.3%	voxel size	<1 mm (isotropic)	1	7.7%
				1 mm (isotropic)	12	92.3%
				other	0	0.0%
2D SE-T1w (post-Gd)	26	56.5%	slice thickness	≤3 mm	10	38.5%
			slice thickness	>3 mm	16	61.5%
			gap	Yes	11	42.3%
			gap	No	15	57.7%
			delay	≤5′	11	42.3%
			delay	>5′	15	57.7%
3D SE-T1w (post-Gd)	16	34.8%	voxel size	<1 mm (isotropic)	6	37.5%
				1 mm (isotropic)	8	50.0%
				other	2	12.5%
			delay	≤5′	11	68.7%
			delay	>5′	5	31.3%
3D GrE-T1w (post-Gd)	23	50.0%	voxel size	<1 mm (isotropic)	3	13.6%
				1 mm (isotropic)	18	81.8%
				other	1	4.6%
			delay	≤5′	7	31.8%
			delay	>5′	15	68.2%
*T2-weighted*
PD/T2w	1	2.2%	slice thickness	≤3 mm	1	100%
			slice thickness	>3 mm	0	0.0%
			gap	Yes	0	0.0%
			gap	No	1	100.0%
2D T2w	30	65.2%	slice thickness	≤3 mm	15	50.0%
			slice thickness	>3 mm	15	50.0%
			gap	Yes	13	43.3%
			gap	No	17	56.7%
3D T2w	3	6.5%	voxel size	<1 mm (isotropic)	1	33.3%
				1 mm (isotropic)	1	33.3%
				other	1	33.3%
2D FLAIR	12	26.1%	slice thickness	≤3 mm	4	33.3%
			slice thickness	>3 mm	8	66.7%
			gap	Yes	2	16.7%
			gap	No	10	83.3%
3D FLAIR	40	87.0%	voxel size	<1 mm (isotropic)	10	25.0%
				1 mm (isotropic)	24	60.0%
				other	6	15.0%
*Sequences for cortical lesions detection*
2D DIR	3	6.5%	slice thickness	≤3 mm	2	66.7%
			slice thickness	>3 mm	1	33.3%
			gap	Yes	1	33.3%
			gap	No	2	66.7%
3D DIR	14	30.4%	voxel size	<1 mm (isotropic)	2	14.3%
				1 mm (isotropic)	10	71.4%
				other	2	14.3%
2D PSIR	4	8.7%	slice thickness	≤3 mm	2	50.0%
			slice thickness	>3 mm	2	50.0%
			gap	Yes	2	50.0%
			gap	No	2	50.0%
3D PSIR	3	6.5%	voxel size	<1 mm (isotropic)	0	0.0%
				1 mm (isotropic)	3	100%
				other	0	0.0%
None	23	50.0%
*Sequences for optic nerves evaluation*
STIR-T2w	34	73.9%	slice thickness	≤3 mm	31	91.2%
			slice thickness	>3 mm	3	8.8%
			gap	Yes	10	29.4%
			gap	No	24	70.6%
Post-Gd Fat-Sat T1w	22	47.8%	slice thickness	≤3 mm	22	100%
			slice thickness	>3 mm	0	0.0%
			gap	Yes	5	22.7%
			gap	No	17	77.3%
None	8	17.4%
*Additional sequences*
DWI	44	95.6%
GrE-T2*	17	37.0%	slice thickness	≤3 mm	4	23.5%
			slice thickness	>3 mm	13	76.5%
			gap	Yes	8	47.1%
			gap	No	9	53.9%
2D SWI	12	26.1%	slice thickness	≤3 mm	9	75.0%
			slice thickness	>3 mm	3	25.0%
			gap	Yes	2	16.7%
			gap	No	10	83.3%
3D SWI	15	32.6%	voxel size	<1 mm (isotropic)	4	26.7%
				1 mm (isotropic)	9	60.0%
				other	2	13.3%
None	1	2.2%
SPINE MRI
*MRI SEQUENCES*	*Number of Affirmative Answers*	*Percentage*	*Additional Questions*		*Number of Answers*	*Percentage*
*T2-weighted*
T2w	41	89.1%	acquisition plane	sagittal	41	100%
			acquisition plane	axial	17	41.5%
			slice thickness on sagittal acquisition	≤3 mm	39	95.1%
			slice thickness on sagittal acquisition	>3 mm	2	4.9%
			gap on sagittal acquisition	Yes	14	34.1%
			gap on sagittal acquisition	No	27	65.9%
PDw	2	4.3%	acquisition plane	sagittal	2	100.0%
			acquisition plane	axial	0	0.0%
			slice thickness on sagittal acquisition	≤3 mm	1	50.0%
			slice thickness on sagittal acquisition	>3 mm	1	50.0%
			gap on sagittal acquisition	Yes	2	100.0%
			gap on sagittal acquisition	No	0	0.0%
STIR-T2w	42	91.3%	acquisition plane	sagittal	42	100.0%
			acquisition plane	axial	2	4.7%
			slice thickness on sagittal acquisition	≤3 mm	38	90.5%
			slice thickness on sagittal acquisition	>3 mm	4	9.5%
			gap on sagittal acquisition	Yes	14	33.3%
			gap on sagittal acquisition	No	28	66.7%
*T1-weighted and inversion recovery*
PSIR	2	4.3%	acquisition plane	sagittal	2	100%
			acquisition plane	axial	0	0.0%
			slice thickness on sagittal acquisition	≤3 mm	2	100%
			slice thickness on sagittal acquisition	>3 mm	0	0.0%
			gap on sagittal acquisition	Yes	1	50.0%
			gap on sagittal acquisition	No	1	50.0%
2D SE-T1w (pre-Gd)	26	56.5%	acquisition plane	sagittal	26	100%
			acquisition plane	axial	3	11.5%
			slice thickness on sagittal acquisition	≤3 mm	23	88.5%
			slice thickness on sagittal acquisition	>3 mm	3	11.5%
			gap on sagittal acquisition	Yes	11	42.3%
			gap on sagittal acquisition	No	15	57.7%
3D GrE-T1w (pre-Gd)	2	4.3%	acquisition plane	sagittal	2	100%
			acquisition plane	axial	1	50.0%
			slice thickness on sagittal acquisition	≤3 mm	2	100%
			slice thickness on sagittal acquisition	>3 mm	0	0.0%
			gap on sagittal acquisition	Yes	0	0.0%
			gap on sagittal acquisition	No	2	100%
2D SE-T1w (post-Gd)	42	91.3%	acquisition plane	sagittal	41	100%
			acquisition plane	axial	13	31.7%
			slice thickness on sagittal acquisition	≤3 mm	37	90.2%
			slice thickness on sagittal acquisition	>3 mm	4	9.8%
			gap on sagittal acquisition	Yes	16	39.0%
			gap on sagittal acquisition	No	25	61.0%
			delay	≤5′	19	47.5%
			delay	>5′	21	52.5%
3D GrE-T1w (post-Gd)	3	6.5%	acquisition plane	sagittal	2	66.7%
			acquisition plane	axial	2	66.7%
			slice thickness on sagittal acquisition	≤3 mm	2	100%
			slice thickness on sagittal acquisition	>3 mm	0	0.0%
			gap on sagittal acquisition	Yes	0	0.0%
			gap on sagittal acquisition	No	2	100%
			delay	≤5′	1	33.3%
			delay	>5′	2	66.7%

SE = spin-echo; GrE = gradient-echo; FLAIR = fluid attenuated inversion recovery; DIR = double inversion recovery; PSIR = phase sensitive inversion recovery; Fat-Sat = fat saturated; DWI = diffusion weighted imaging; SWI = susceptibility weighted imaging; PD = proton density; STIR = short tau inversion recovery; Gd = gadolinium.