API |
active pharmaceutical ingredient |
ATMP |
advanced therapy medicinal product |
BCA |
bicinchoninic acid assay |
BPyV |
bovine polyomavirus |
BSA |
bovine serum albumin |
CD |
cluster of differentiation |
CHUV |
Centre hospitalier universitaire Vaudois |
CPP |
critical process parameter |
CQA |
critical quality attribute |
DMEM |
Dulbecco’s modified Eagle medium |
DMSO |
dimethyl sulfoxide |
DNA |
deoxyribonucleic acid |
EBV |
Epstein-Barr virus |
EC |
European Commission |
ECACC |
European collection of authenticated cell cultures |
EDQM |
European Directorate for the Quality of Medicines & Healthcare |
EDTA |
ethylenediaminetetraacetic acid |
ELISA |
enzyme-linked immunosorbent assay |
EOPCB |
end of production cell bank |
EP |
European Pharmacopoeia |
ESC |
embryonic stem cells |
FACS |
fluorescence activated cell-sorting |
FBS |
fetal bovine serum |
FDA |
US Food and Drug Administration |
FPC |
fibroblast progenitor cells |
FT |
freeze-thaw |
GMP |
good manufacturing practices |
HAV |
hepatitis A virus |
HBV |
hepatitis B virus |
HBoV |
human bocavirus |
hCMV |
human cytomegalovirus |
HCV |
hepatitis C virus |
HHV |
human herpes virus |
HIV |
human immunodeficiency virus |
HPV |
human papilloma virus |
HTLV |
human T-cell lymphotropic virus |
IPC |
in-process control |
KIPyV |
KI polyomavirus |
KPP |
key process parameter |
LYO |
lyophilizate |
MCB |
master cell bank |
MoA |
mechanism of action |
MSC |
mesenchymal stem cells |
PBB |
Progenitor Biological Bandage |
PBS |
phosphate-buffered saline |
PCB |
parental cell bank |
PDT |
population doubling time |
PDV |
population doubling value |
PPC |
post-process control |
RH |
relative humidity |
SD |
standard deviation |
SV40 |
simian virus 40 |
TEM |
transmission electron microscopy |
TEP |
tissue engineering product |
TrSt |
standardized transplant product |
USA |
United States of America |
WCB |
working cell bank |
WUPyV |
WU polyomavirus |