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. 2021 Aug 4;13(16):3926. doi: 10.3390/cancers13163926

Table 2.

Relevant studies on survival following ablation of recurrent colorectal liver metastases after hepatectomy within 10 years.

Author/Year Type of Study Number of Patients/Lesions Approach of Ablation Mean/Median Tumor Size (cm) Mean/Median Tumor Number Median Follow-Up Period in Months Local Tumor Progression Rate (%) Liver Limited Recurrence (%) Repeat Local Treatment for Liver Limited Recurrence (%) 3-y OS (%) 5-y OS (%)
Fan/2020 [143] Retrospective 144/258 Percutaneous RFA 2.6 5.1 28.6 7 79.2 * n/a n/a 27.1
Zimmermann/2020 [43] Retrospective 23/29 Percutaneous RFA n/a n/a 26 n/a 74 n/a 57 24
Schullian/2020 [44] Retrospective 64/217 Percutaneous RFA § 2.7 2 21 11.5 48.4 * 48.4 46.2 34.8
Mao/2019 [144] Retrospective 61/114 Percutaneous RFA # 2.7 2 28.9 16.7 54.1 52 n/a 33
Odisio/2018 [115] Retrospective 49/59 Percutaneous RFA, MWA, and Cryoablation n/a n/a 28 5.1 n/a n/a 78 n/a
Dupré/2017 [45] Retrospective 33/n/a Open or percutaneous RFA, MWA, and IRE 2 2 36.2 n/a 54.5 88.9 30.4 n/a
Sofocleous/2011 [47] Retrospective 56/71 Percutaneous RFA 1.9 1.3 22 50.7 n/a 47.2 41 n/a

Abbreviations—n/a: not available; OS: overall survival, *: Intrahepatic distant metastases; §: stereotactic radiofrequency ablation. Retreat with RFA only. #: Resectable CLM.