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AKAP79 binds calcineurin, protein kinase A and NFAT1. (A) Pull down of NFAT1-GFP revealed the presence of calcineurin, the regulatory subunit of protein kinase A, denoted PKA (RII), and AKAP79. The signalosome remained intact after store depletion with thapsigargin (2 μm, applied in Ca2+-free external solution). (B) Aggregate data from three independent experiments as in Panel A are shown.
