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. 2021 Aug 10;11(8):1440. doi: 10.3390/diagnostics11081440

Table 3.

OVA1 Performance Stratified by Race.

OVA1 Performance When CA125 Is Low-Risk * by Race
Menopausal Status N Sensitivity (%, n/N) Specificity (%, n/N) PPV (%, n/N) NPV (%, n/N) LR+ LR−
White/Caucasian All 1492 64.62% 67.90% 8.40% 97.68% 2.01 0.52
42/65 969/1427 42/500 969/992
Pre 848 54.55% 75.18% 5.53% 98.42% 2.20 0.60
12/22 621/826 12/217 621/631
Post 644 69.77% 57.90% 10.60% 96.40% 1.66 0.52
30/43 348/601 30/283 348/361
Black/African American All 283 41.67% 79.32% 8.33% 96.79% 2.02 0.74
5/12 211/266 5/60 211/218
Pre 195 37.50% 82.07% 8.33% 96.79% 2.09 0.76
3/8 151/184 3/36 151/156
Post 88 50.00% 73.17% 8.33% 96.77% 1.86 0.68
2/4 60/82 2/24 60/62

PPV, positive predictive value; NPV, negative predictive value; LR+, positive likelihood ratio; LR−, negative likelihood ratio. Cancer prevalence is 4.5% (104/2305). * Low-risk CA125, 67 U/mL for premenopausal subjects; 35 U/mL for postmenopausal or unknown subjects.