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. 2021 Aug 7;18(16):8371. doi: 10.3390/ijerph18168371

Table 3.

Effect of changes in periodontal parameters at different stages (at baseline and at 1-month, 3-month and 6-month follow-up) by group among patients with T2DM.

EG (n = 35) CG (n = 33)
Diff ± SD Diff ± SD Effect Size d β (95% CI)
PPD
 Group (EG) × Time (second) −0.5 ± 0.4 −0.2 ± 0.3 0.61 −0.2 (−0.41, −0.08)
 Group (EG) × Time (third) −0.5 ± 0.5 −0.4 ± 0.4 0.22 −0.1 (−0.34, 0.07)
 Group (EG) × Time (fourth) −0.4 ± 0.5 −0.3 ± 0.5 0.18 −0.1 (−0.36, 0.11)
 Effect size a 1.19 0.73
 Effect size b 0.94 0.85
 Effect size c 0.80 0.67
CAL
 Group (EG) × Time (second) −0.4 ± 0.4 −0.1 ± 0.3 0.59 −0.2 (−0.39, −0.06)
 Group (EG) × Time (third) −0.3 ± 0.4 −0.2 ± 0.4 0.14 −0.1 (−0.30, 0.14)
 Group (EG) × Time (fourth) −0.3 ± 0.5 −0.2 ± 0.5 0.15 −0.1 (−0.37, 0.16)
 Effect size a 0.89 0.41
 Effect size b 0.69 0.55
 Effect size c 0.59 0.43
GI
 Group (EG) × Time (second) −0.8 ± 0.5 −0.8 ± 0.8 0.01 0.0 (−0.27, 0.30)
 Group (EG) × Time (third) −0.9 ± 0.7 −1.1 ± 0.6 0.30 0.2 (−0.16, 0.50)
 Group (EG) × Time (fourth) −0.8 ± 0.8 −1.0 ± 0.8 0.22 0.2 (−0.17, 0.51)
 Effect size a 1.56 1.05
 Effect size b 1.24 1.67
 Effect size c 1.03 1.22
PI
 Group (EG) × Time (second) −0.6 ± 0.6 −0.8 ± 0.8 0.24 0.2 (−0.12, 0.46)
 Group (EG) × Time (third) −0.7 ± 0.7 −1.0 ± 0.9 0.44 0.3 (−0.04, 0.63)
 Group (EG) × Time (fourth) −0.7 ± 0.7 −1.0 ± 0.8 0.32 0.2 (−0.14, 0.58)
 Effect size a 1.07 0.98
 Effect size b 0.93 1.17
 Effect size c 0.92 1.17
BOP (%)
 Group (EG) × Time (second) −26.5 ± 19.5 −20.5 ± 26.0 0.26 −5.7 (−15.98, 3.88)
 Group (EG) × Time (third) −29.5 ± 23.0 −28.7 ± 26.4 0.03 −1.6 (−12.66, 9.47)
 Group (EG) × Time (fourth) −30.4 ± 26.9 −26.1 ± 29.8 0.15 −0.3 (−12.04, 11.35)
 Effect size a 1.36 0.79
 Effect size b 1.28 1.09
 Effect size c 1.13 0.88

Time (second): 1-month follow-up; Time (third): 3-month follow-up; Time (fourth): 6-month follow-up; SD: standard deviation; CI: confidence interval. Difference between baseline and follow-up within group. a Effect size calculated as mean difference between baseline and 1-month follow-up. b Effect size calculated as mean difference between baseline and 3-month follow-up. c Effect size calculated as mean difference between baseline and 6-month follow-up. d Effect size calculated as mean difference of change between baseline and follow-up measurements between EG and CG. Β (95% CI): adjusted for age, gender, education level, BMI, and duration of diabetes in linear regression using generalized estimating equations (GEEs); Reference: Control group × Time (baseline).