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. 2021 Aug 13;12(8):1243. doi: 10.3390/genes12081243

Table 2.

Genomic positions of SNPs that exceeded the cutoff threshold (Z(FST) ≥ 7.68) for divergence in birth weight and adjacent candidate genes within a 2 Mb window.

Rs Identifier Chr Position MAF Z(FST) Permutation
p Value 1 		Association
p Value 2 		Candidate Genes 3
rs426652102 1 95369397 0.335 10.68 0.0006 0.004 TBX15, SPAG17
rs409727057 1 124117118 0.220 7.97 0.001 0.003 CLDN17, GRIK1
rs423222301 2 5472326 0.301 8.88 0.0006 0.015 BRINP1, TLR4
rs419514091 2 60044110 0.369 8.17 0.0006 0.116 PCKS5, RFK, ENSOARG00000012533
rs428614465 3 27732721 0.492 7.68 0.0009 <0.0001 MATN3, OSR1, WDR35, TTC32
rs417060060 3 160252310 0.446 10.61 0.0003 0.001 SLC16A7, LRIG3
rs413547561 5 31477570 0.481 8.21 0.001 0.144 PRR16, FAM170A
rs413364871 6 51650705 0.301 10.06 0.0003 0.006 --
rs427385309 8 64075259 0.276 8.00 0.0006 0.156 CITED2, U5, NMBR
rs406649973 13 54940415 0.444 9.61 0.0003 0.041 LAMA5, CDH28, CDH4
rs419112095 13 54219758 0.295 8.03 0.0009 0.166 LAMA5, RPS21, ADRM1
rs410323459 14 39415649 0.328 8.00 0.001 0.0006 URI1, HYDIN, CMTR2, POP4
rs423237115 16 56144068 0.412 11.67 0.0003 0.014 MYO10
rs413049228 16 18186560 0.134 7.84 0.009 0.058 ZSWIM6, SMIM15
rs413966946 17 6026379 0.465 9.34 0.0006 0.006 FAM160A1, GATB, SH3D19
rs430430903 19 33088813 0.289 8.08 0.0006 0.046 SUCLG2, ENSOARG00000010424
rs417719085 22 42323039 0.444 10.23 0.0003 0.002 CPXM2, GPR26, ACADSB
rs412781362 23 41177245 0.127 8.07 0.0009 0.001 LAMA1, PTPRM, RAB12
rs421209784 24 18748352 0.086 7.84 0.0009 0.001 DNAH3, LYRM1, TMEM159
rs429736586 25 41911462 0.348 8.03 0.0003 0.064 GDF2, GDF10, PTPN20

1 p-value resulting from permutation-based test of FST values and subsequent adjustment for genomic inflation; 2 p-value resulting from association analysis of the respective SNP with birth weight; 3 Gene names in bold = functional candidate genes, underlined = positional candidate genes, only italic = closest up- and downstream-located genes within a 2 Mb window, Chr = chromosome, MAF = minor allele frequency, Z(FST) = SNP-specific Z-transformed fixation index.