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. 2021 Aug 13;12(8):1243. doi: 10.3390/genes12081243

Table 3.

Genomic positions of SNPs that exceeded the cutoff threshold (Z(FST) ≥ 6.99) for divergence in weaning weight and adjacent candidate genes within a 2 Mb window.

Rs Name Chr Position MAF Z(FST) Permutation
p-Value 1
Association
p-Value 2
Candidate Genes 3
rs401497638 1 226047403 0.274 7.30 0.170 0.002 IL12A, IQCJ
rs402362274 2 4014386 0.194 8.80 0.003 0.015 MEGF9, CDK5RAP2, BRINP1
rs427650461 2 8985061 0.259 7.90 0.003 0.018 TNFSF15, TMEM268
rs405054059 2 236085906 0.354 7.69 0.004 0.177 FABP3, MATN1, PTPRU
rs420573745 3 70227376 0.500 8.59 0.003 0.077 ASB3, CHAC2
rs422502823 3 124010853 0.408 8.47 0.003 0.039 MGAT4C, C12orf50
rs425747978 3 191139722 0.269 7.90 0.003 0.067 SOX5, BCAT1, ETNK1
rs410754805 3 182669294 0.341 7.00 0.003 0.044 RESF1, AMN1
rs429678680 5 3076397 0.224 8.10 0.003 0.278 MEF2B, HAPLN4, NCAN, WNT9A, WNT3A, PRSS38, SNAP47
rs418926568 6 86505675 0.381 7.00 0.004 0.120 SLC4A4, GC
rs401888979 10 25115607 0.219 8.10 0.003 0.002 POSTN, RFXAP, SERTM1
rs428497629 10 59974520 0.263 7.64 0.004 0.006 SLITRK1, SLITRK6
rs426943634 12 12266633 0.436 7.60 0.003 0.009 RGS18, BRINP3
rs413169429 13 74924747 0.303 8.38 0.003 0.009 EYA2, MMP9, TNNC2, TP53RK, SLC13A3, SLC2A10
rs411451096 15 74597812 0.399 7.36 0.003 0.128 ACP2, LRP4, DGKZ, CREB3L1, MDK
rs430684800 18 36936501 0.322 7.01 0.003 0.009 NOVA1, FOXG1
rs426036565 18 55537048 0.414 6.99 0.003 0.495 FBLN5, TC2N, TRIP11
rs410079568 20 23394498 0.470 8.23 0.003 0.143 TFAP2B, PKHD1
rs421690996 22 5090223 0.345 7.03 0.003 0.026 PCDH15, U3, SYCE1
rs400432841 25 41241866 0.459 8.23 0.003 0.039 BMPR1A, GDF10, GDF2, GLUD1, U6, SHLD2

1 p-value resulting from permutation-based test of FST values and subsequent adjustment for genomic inflation; 2 p-value resulting from association analysis of the respective SNP with weaning weight; 3 Gene names in bold = functional candidate genes, underlined = positional candidate genes, only italics = closest up- and downstream-located genes within a 2 Mb window, Chr = chromosome, MAF = minor allele frequency, Z(FST) = SNP-specific Z-transformed fixation index.