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. 2021 Jul 29;12(8):1170. doi: 10.3390/genes12081170

Table 4.

Gene Ontology (GO) terms and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways significantly enriched (p < 0.05) for genes associated with body weight.

Category Term_ID Term Count % p-Value Genes
KEGG_PATHWAY gga04010 MAPK signaling pathway 21 3.0043 0.00 MAP2K3, MAP2K4, MAP3K3, TGFB2, IL1R1, BDNF, NFATC3, MAPK8IP3, TGFBR1, MAPK8IP1, PPP3CA, FGF7, TAOK1, GNA12, MKNK2, RAC2, MAPT, SOS1, SOS2, MAP4K3, MAP4K4
KEGG_PATHWAY gga04530 Tight junction 9 1.2876 0.03 PPP2R2B, MYH1E, MYH1F, MYH1D, PPP2R2A, MYH1A, MYH1B, AMOTL1, MYH10
GOTERM_MF_DIRECT GO:0003774 Motor activity 6 0.8584 0.01 MYH1E, MYH1F, MYH1A, MYH1B, MYH10, MYO1F
GOTERM_MF_DIRECT GO:0001077 Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding 13 1.8598 0.02 ARNT2, MYOCD, PLAG1, NFATC3, EBF2, NRF1, HIF1A, MEOX1, ELF1, NFIA, TBX20, TP63, ZNF750
GOTERM_MF_DIRECT GO:0004702 Receptor signaling protein serine/threonine kinase activity 7 1.0014 0.02 MAP3K3, MAP2K4, TGFB2, BMPR2, TAOK1, TGFBR1, MAP4K4
GOTERM_BP_DIRECT GO:0045944 Positive regulation of transcription from RNA polymerase II promoter 34 4.8641 0.01 RB1, RNASEL, BMPR2, PID1, KDM1A, TNKS, PLAG1, GATA4, TCF20, LDB2, MYSM1, HIF1A, NPAS2, ABRA, SPIC, PPP3CA, EPCAM, CREB3L1, TBX20, CYTL1, PPARGC1A, E2F7, TP63, NCOA1, XRCC6, AUTS2, LMO4, DAB2IP, ARNT, EBF2, ASH1L, BMP5, NFIA, CDH13
GOTERM_BP_DIRECT GO:2001235 Positive regulation of apoptotic signaling pathway 5 0.7153 0.01 DAB2IP, PTEN, CASP2, TP63, TGFBR1

%: the percentage of genes associated with particular annotation terms in the total input gene list; MF: Molecular function; BP: Biological process.