Table 1.

List of MAPK members in human and commonly used animal models.

MAPK Members	Homo sapiens	Mus musculus	Drosophila melanogaster	Caenorhabditis elegans	Danio rerio
MAP4K	MAP4K1–7	Mapk4k 1/2/3/5/	Hppy, Msn		-
MAP3K	RAF (A, B, C), MOS, MEKK1–4, MLK 1/2/3/4/7, PTK, DLK, LZK, TAO, ASK, TAK1, TPL2	Raf (A, B, C), Mos, Mekk1–4, Mlk 1/2/3/4/7, Ptk, Dlk, Lzk, Tao, Ask, Tak1, Tpl2	Draf, Dmekk, Slpr, Wnd, Tao, Dask, Dtak1	Lin-45	Raf 1a/1b, c-Mos, cb135, Zak, zakl, Ask1, Tak1
MAP2K	MEK1/2, MKK3/4/5/6/7	Mek1/2, Mkk3/4/5/6/7	Lic, Dmkk4, Hep	Mek-2	Mek1/2, Mkk3/4/7
MAPK	JNK1–3, p38α/β/γ/δ, ERK1/2/3/4/5/6/7/8	Jnk1–3, p38 α/β/γ/δ, ERK1/2/3/4/5/6/7/8	Bsk, ERK-A	Mpk-1	Jnk1/2/3, Zp38a/b, Erk1/2/3/4/5/6/7