Table 3.
Incidences and hazard ratio of colorectal cancer estimated by colorectum site compared between cohorts with and without hemorrhoids.
| Site of CRC | Hemorrhoids | Crude HR (95% CI) |
Adjusted HR (95% CI) |
|||
|---|---|---|---|---|---|---|
| No | Yes | |||||
| Event | Rate # | Event | Rate # | |||
| Ascending colon (ICD-9-CM 153.0, 153.4-6) | 13 | 0.05 | 21 | 0.08 | 1.49 (0.75, 2.97) | 1.34 (0.67, 2.69) |
| Transverse colon (ICD-9-CM 153.1) | 4 | 0.02 | 5 | 0.02 | 1.18 (0.32, 4.41) | 1.08 (0.29, 4.07) |
| Descending colon (ICD-9-CM 153.2, 153.7) | 3 | 0.01 | 10 | 0.04 | 3.13 (0.86, 11.4) | 2.83 (0.78, 10.3) |
| Sigmoid colon (ICD-9-CM 153.3) | 21 | 0.08 | 43 | 0.17 | 1.92 (1.14, 3.24) * | 1.79 (1.06, 3.02) * |
| Rectum (ICD-9-CM 154.0-1) | 34 | 0.14 | 86 | 0.33 | 2.40 (1.61, 3.57) ** | 2.20 (1.48, 3.28) ** |
| Other (ICD-9-CM 153.8-9, 154.2-3, 154.8) | 18 | 0.07 | 39 | 0.15 | 2.08 (1.19, 3.64) | 1.86 (1.06, 3.26) |
| Unknown | 45 | 0.17 | 133 | 0.51 | 2.99 (1.97, 3.66) ** | 2.76 (1.85, 3.67) ** |
Rate #: incidence rate per 1000 person-years; HR, hazard ratio. Adjusted HR: estimated after controlling for sex, age, and comorbidity. * p < 0.05, ** p < 0.001.