Table 3.

Effect of low-dose decitabine on cytokines in patients with ITP (N = 32)

Cytokine, pg/mL	Before decitabine	After decitabine	P
IL-1β	0.34 (0.27-0.52)	0.35 (0.24-0.44)	.111
IL-2	0.63 (0.44-0.80)	0.72 (0.53-0.90)	.027
IL-4	0.05 (0.04-0.06)	0.04 (0.04-0.06)	.536
IL-6	1.38 (1.00-3.25)	1.07 (0.76-1.48)	.005
IL-8	4.88 (2.71-10.38)	3.54 (2.34-7.83)	.029
IL-10	0.78 (0.38-1.49)	0.63 (0.41-0.79)	.410
IL-12	0.37 (0.26-0.49)	0.33 (0.24-0.41)	.026
IL-13	0.63 (0.40-0.82)	0.60 (0.43-0.85)	.733
IL-17a	2.01 (1.48-3.03)	1.86 (1.09-2.50)	.046
IFN-γ	8.82 (6.11-13.12)	6.06 (4.20-9.61)	.005
TNF-α	6.15 (4.72-9.25)	5.75 (4.32-6.89)	.014
TGF-β	747.30 (616.00-1126.00)	1109.00 (664.40-1976.00)	.029

Data are expressed as median (interquartile range).