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. 2021 Aug 3;10(8):1976. doi: 10.3390/cells10081976

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overview of the one-carbon metabolism. Abbreviations: dihydrofolate reductase (DHFR); serine hydroxymethyltransferase (SHMT); methylenetetrahydrofolate reductase (MTHFR); multiple methyltransferases (MT); S-adenosylhomocysteine hydrolase (SAHH); cystathionine beta-synthase (CBS); methionine synthase (MTR); betaine aldehyde dehydrogenase (BAD); methionine adenosyltransferase (MAT); betaine homocysteine S-methyltransferase (BHMT); cystathionine γ-lyase (CSE); methylenetetrahydrofolate dehydrogenase (MTHFD).